The Spirit Molecule investigates dimethyltryptamine (DMT), an endogenous psychoactive compound, which exists in humans and numerous species of plants and animals. The documentary traces Dr. Rick Strassman's government-sanctioned, human DMT research and its many trials, tribulations, and inconceivable realizations. A closer examination of DMT's effects through the lens of two traditionally opposed concepts, science and spirituality, The Spirit Molecule explores the connections between cutting-edge neuroscience, quantum physics, and human spirituality. Strassman's research, and the experiences of the human test subjects before, during, and after the intense clinical trials, raises many intriguing questions. A variety of experts voice their unique thoughts and experiences with DMT within their respective fields. As Strassman's story unfolds, the contributors weigh in on his remarkable theories, including the synthesis of DMT in our brain's pineal gland, its link to near-death & alien-abduction experiences, the history/future of psychedelics, and the uncanny likeness to ancient religious texts describing prophets with DMT-like experiences. Additionally, the intriguing similarities to the "many-worlds" interpretation of quantum mechanics lead to other fascinating discoveries. The experts offer a comprehensive collection of information, opinions, and speculation to help understand the nature of the DMT experience, and its role in human culture and the life force of our planet. Due to the profound nature, and visual phantasmagoria, of the DMT experience, the visual landscape of the film features stunning visualizations from Scott Draves (Electric Sheep), as well as a cutting-edge motion graphics, which demonstrate DMT's conceptual link to human evolution, construction of the universe, advanced neuroscience, and other alluring theories. Finally, stylized scenes reminiscent of Rod Sterling's famous Twilight Zone bookends, Joe Rogan (actor/comedian) serves as tour guide, helping navigate the expansive realms of Strassman's DMT universe. Dimethyltryptamine: a simple molecule with enormous implications. The Spirit Molecule's subtle combination of science, spirituality, and philosophy results in an abundance of incredible ideas and theories that could alter the way we understand the universe and our relationship to it.